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What Is Hydroxytyrosol?
If you’ve ever read about the health benefits of olive oil, you might have come across the term hydroxytyrosol. This is a powerful polyphenol—a plant-based compound—known for its anti-inflammatory and heart-protective effects. It’s one of the reasons olive oil is celebrated as a superfood.
But here’s the important part: hydroxytyrosol is just one of many beneficial compounds in olive oil. Focusing only on it means missing the bigger picture. Olive oil’s health benefits come from a combination of nutrients working together, not from a single ingredient.
For example, oleocanthal is another polyphenol in olive oil with strong anti-inflammatory properties—so much so that it’s often compared to ibuprofen in how it works in the body. Then there’s oleuropein, found in greater amounts in fresh olive oil, which acts as a powerful antioxidant and helps protect your arteries from damage. And we can’t forget oleic acid, the main healthy fat in olive oil, linked to lowering blood pressure, improving cholesterol, and reducing the risk of heart disease.
This is why the Mediterranean diet—rich in extra virgin olive oil—has been so strongly linked to better health. No major studies have shown that isolating hydroxytyrosol alone delivers the same benefits. It’s the whole food synergy that counts.
So, when brands like Dr. Gundry’s Olive Oil market themselves solely on “high polyphenol content,” it’s mostly a marketing tactic. Good-quality extra virgin olive oil—whether high or moderate in polyphenols—can still provide outstanding health benefits.
Health Benefits of Olive Oil

Olive Oil and Heart Health
Olive oil is one of the most researched foods for cardiovascular protection. Studies show that just two tablespoons (about 25 grams) daily can lower your risk of heart disease and even reduce overall mortality.
The magic isn’t just in the polyphenols—it’s mainly because the unsaturated fats in olive oil replace less healthy saturated fats like butter. This swap leads to better blood pressure control, improved cholesterol levels, and reduced artery inflammation.
Olive Oil and Diabetes
Regular olive oil consumption is linked to better blood sugar control and a reduced risk of type 2 diabetes. Research shows it can lower blood sugar and HbA1c levels in people with diabetes. However, its benefits are similar to other healthy oils like fish oil or avocado oil, suggesting that the healthy fats—not just the polyphenols—are driving these results.
Olive Oil and Cancer Prevention
Olive oil appears most protective against breast cancer, with several studies showing lower risk among women who consume it regularly. The evidence for other cancers is mixed: there may be benefits for esophageal, pancreatic, and ovarian cancers, but little effect has been seen for stomach or colorectal cancers.
Olive Oil and Brain Health
Some research suggests olive oil may help support brain function, particularly in people with mild cognitive impairment or early Alzheimer’s. In one small study, higher-polyphenol olive oils produced slightly better results. However, these effects were modest, required large daily doses (about 50 ml), and were not seen in healthy adults.
Olive Oil for Skin and Hair
While olive oil is often promoted as a beauty remedy, the science is limited. It may help when combined with other ingredients—such as aloe vera for eczema, or honey and beeswax for psoriasis—but olive oil alone hasn’t been proven to prevent wrinkles, stretch marks, or hair damage.
Olive Oil and Weight Loss
Despite the hype, olive oil isn’t a magic weight-loss food. Studies show it doesn’t significantly reduce body weight, body fat, or waist circumference compared to placebo. In some cases, it may slightly increase fat mass if not balanced within total calorie intake.
The Bottom Line
Olive oil is a genuine health booster—especially for your heart, blood sugar control, and possibly breast cancer prevention. But these benefits come mainly from its healthy fats, not just from compounds like hydroxytyrosol. That means you don’t need to pay top dollar for “super high polyphenol” olive oil to enjoy its rewards.
Many other plant-based oils rich in unsaturated fats—like avocado oil—offer similar cardiovascular advantages. Still, a fresh, good-quality extra virgin olive oil can add flavor, nutrients, and health benefits to your diet when used regularly.
How to Choose the Best Olive Oil
- Go Extra Virgin: This means the oil is mechanically pressed without chemicals or heat, preserving its nutrients.
- Check the Harvest Date: Choose bottles less than a year old for peak freshness.
- Use It Quickly: Once opened, aim to finish within two to three months.
- Pick the Right Packaging: Dark glass or tins protect against light and heat damage.
- Know the Source: Single-estate or region-specific oils are often more trustworthy than blends from multiple countries.
- Taste Test: Quality olive oil should taste fruity, slightly bitter, and peppery—signs of freshness and antioxidants.
- Be Wary of Bargains: True extra virgin olive oil isn’t cheap—ultra-low prices often mean low quality.
Dr. Brian’s favorite EVOOs (no particular order)
- Cobram Estate California Select
- Graza Sizzle/Drizzle
- Kirkland Signature
- Laconiko Ultra Premium
- Lucini Premium Select Organic
Learn more about
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- Mediterranean diet: an overview
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Citations
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See also
- Olive Oil and HydroxytyrosolOlive oil benefits your health mainly due to its healthy fats, so you don’t need pricey high-polyphenol varieties to reap the benefits.
- The REAL Benefits of CollagenThere are three types of collagen (I, II, III) and two main ways to take them (native vs peptides). The best type depends on your goal.
- Magnesium Sprays & Epsom Baths: Do They Work?Magnesium sprays and Epsom baths might feel nice, but research shows they’re not a reliable way to boost magnesium or treat health issues.
- Are Gummy Probiotics a Scam?Gummy probiotics usually only include Bacillus coagulans and Bacillus subtilis since other strains can’t survive the manufacturing process.
- C15 Supplements EXPOSEDPentadecanoic acid (C15) is not well-studied, and there’s no evidence showing they’re more effective than fish oil or beneficial for aging.