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Creatine Health Benefits: Myths vs Reality

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We all know creatine is one of the most reliable supplements for improving strength and athletic performance. The science behind that claim is strong and consistent. But what about the other promises you might hear — like sharper brain function, a better mood, or even faster weight loss? Let’s break down what the research really says.

Creatine Health Claims

health-benefits-of-creatine
Researched health benefits of creatine

Creatine and Brain Health

Creatine is sometimes promoted as a natural “brain booster,” but the evidence doesn’t really back that up for most healthy people. For example, studies in young adults show that taking between 5 to 20 grams per day for six weeks doesn’t improve thinking skills or memory.

Some reviews suggest there may be very small benefits for older adults or those in less-than-optimal health, especially when it comes to short-term memory. Vegetarians, who naturally get less creatine from food, may also notice a slight bump. Still, these effects are minor and don’t go much further than memory support.

When researchers looked at people with more serious cognitive problems, the results were even less promising. Studies on age-related memory decline, Parkinson’s disease, and schizophrenia found no meaningful benefits, even when creatine was taken for over a year.

So, if you’re healthy and looking for a brain boost, creatine probably won’t deliver. At best, certain groups — like vegetarians or older adults — might see a very small improvement in memory, but that’s about it.

Creatine and Mood

Another common belief is that creatine can help with depression. The science here is also pretty weak. One small study found that women taking 5 grams a day for eight weeks saw a slightly better response when creatine was combined with the antidepressant escitalopram. But importantly, creatine wasn’t effective on its own — only as a small add-on.

In fact, leading expert organizations, including the World Federation of Societies of Biological Psychiatry and the Canadian Network for Mood and Anxiety Treatments, recommend against using creatine as a treatment for depression. As of now, there’s simply no strong evidence that creatine can act as a standalone antidepressant.

Creatine and Weight Loss

Finally, let’s tackle the idea that creatine helps with weight loss. This is one of the biggest myths out there. Creatine doesn’t burn fat or directly cause weight loss. What it can do is help you work harder in the gym. Over time, that extra effort may lead to burning more calories, but that’s an indirect effect, not the creatine itself.

More often, creatine is linked to weight gain — but in a positive way. It helps build lean muscle, which can make your body look more toned and athletic. If your main goal is fat loss, creatine won’t do the job on its own. It’s best viewed as a performance enhancer, not a fat burner.

What is Creatine?

Creatine is best known as a workout supplement, but it’s also something your body naturally produces and stores—mostly in your muscles. You can get it through food as well, especially from red meat and fish. Because creatine is found almost entirely in animal products, people who follow vegetarian or vegan diets tend to have lower levels. Their bodies rely mostly on what they can make on their own, which usually isn’t as much as what meat eaters get from food.

That’s one reason creatine supplements can have a bigger impact on people who don’t eat meat. Since they start at a lower baseline, the boost in energy and performance feels more noticeable. Think of creatine as your body’s backup battery. Your cells run on ATP, the fuel that powers every move you make. But ATP burns out quickly during short, intense bursts—like sprinting, jumping, or lifting heavy weights. That’s where creatine steps in, recharging your energy supply so you can keep going.

This is why athletes, bodybuilders, and everyday gym-goers use creatine. By keeping your muscles topped up, you can train harder, recover faster, and get more out of every workout.

How to Take Creatine

If you want to fill your muscles with creatine quickly, you can follow a “loading phase.” This usually means taking about 20 grams a day, split into smaller doses, for 5 to 7 days. After that, you drop down to a maintenance dose of 3 to 5 grams daily. Another option is to skip the loading phase and simply take 3 grams a day. It works just as well—it just takes a little longer to fully saturate your muscles.

The most effective way to take creatine is as a powder dissolved in water or another liquid. Pills, lozenges, or dry powder don’t absorb as efficiently. For an extra boost, you can take creatine with carbohydrates. The insulin response helps your muscles absorb more.

As for timing, some small studies suggest that taking creatine after a workout may give a slight edge in muscle growth and strength. But larger reviews show that timing doesn’t make much difference in the long run. The key is consistency—take it every day, and your body will get the benefits.

Best Types of Creatine

There’s a lot of debate about which type of creatine is best, but the answer is straightforward: creatine monohydrate. This form has been studied more than any other, it’s proven to be the most effective at raising muscle creatine levels, and it’s usually the most affordable option.

Other forms exist, but the research on them is limited. Di-creatine citrate, for example, dissolves more easily in water, but that doesn’t mean your body absorbs it better. In fact, many alternative forms simply convert into creatine monohydrate once mixed into liquid.

Creatine nitrate is another form that’s often marketed as superior, but clinical studies don’t show it performs any better than monohydrate. At the end of the day, no matter which version you take, your body processes it as creatine, and it behaves the same way once it’s in your system.

Does Creatine Cause Hair Loss?

One of the most common fears about creatine is that it causes hair loss. This idea comes from a single study that suggested creatine might raise levels of DHT, a hormone linked to male-pattern baldness. Since DHT can shrink hair follicles in men who are genetically predisposed, the rumor spread that creatine could speed up balding.

But the evidence doesn’t back that up. Most studies show no meaningful increase in testosterone or DHT when people take creatine. Even when levels do rise slightly, they stay well within the normal range. In fact, a study published in 2025 found no change in DHT and no effect on hair health in men using creatine.

It’s also important to point out that the original study showing a “DHT spike” used an unusually high loading dose—25 grams a day, plus carbs to maximize absorption. That’s far more than what most people would ever take. And to date, no controlled trial has shown actual hair loss caused by creatine. The scattered reports of thinning hair remain anecdotal.

Under normal dosing, creatine doesn’t appear to cause hair loss in any meaningful way. If you’re concerned, it’s best to stick with moderate daily doses and skip extreme loading phases.

Dr. Brian’s Review

Creatine is one of the most well-researched and effective supplements for boosting strength and exercise performance. However, it’s not a magic pill for brain health, mood, or fat loss. The most reliable form is plain creatine monohydrate, which you can easily mix into water, juice, or a smoothie. Timing isn’t critical—before or after your workout both work just fine. And despite the myths, creatine is not likely to make you lose your hair if you use it responsibly.

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Citations

Alves CR, Merege Filho CA, Benatti FB, Brucki S, Pereira RM, de Sá Pinto AL, Lima FR, Roschel H, Gualano B. Creatine supplementation associated or not with strength training upon emotional and cognitive measures in older women: a randomized double-blind study. PLoS One. 2013 Oct 3;8(10):e76301. doi: 10.1371/journal.pone.0076301. PMID: 24098469; PMCID: PMC3789718.

Antonio, J., Candow, D.G., Forbes, S.C. et al. Common questions and misconceptions about creatine supplementation: what does the scientific evidence really show?. J Int Soc Sports Nutr 18, 13 (2021). https://doi.org/10.1186/s12970-021-00412-w

Antonio J, Ciccone V. The effects of pre versus post workout supplementation of creatine monohydrate on body composition and strength. J Int Soc Sports Nutr. 2013 Aug 6;10:36. doi: 10.1186/1550-2783-10-36. PMID: 23919405; PMCID: PMC3750511.

Avgerinos KI, Spyrou N, Bougioukas KI, Kapogiannis D. Effects of creatine supplementation on cognitive function of healthy individuals: A systematic review of randomized controlled trials. Exp Gerontol. 2018 Jul 15;108:166-173. doi: 10.1016/j.exger.2018.04.013. Epub 2018 Apr 25. PMID: 29704637; PMCID: PMC6093191.

Bartholomae E, Knurick J, Johnston CS. Serum creatinine as an indicator of lean body mass in vegetarians and omnivores. Front Nutr. 2022 Sep 16;9:996541. doi: 10.3389/fnut.2022.996541. PMID: 36185683; PMCID: PMC9525150.

Bender A, Koch W, Elstner M, Schombacher Y, Bender J, Moeschl M, Gekeler F, Müller-Myhsok B, Gasser T, Tatsch K, Klopstock T. Creatine supplementation in Parkinson disease: a placebo-controlled randomized pilot trial. Neurology. 2006 Oct 10;67(7):1262-4. doi: 10.1212/01.wnl.0000238518.34389.12. PMID: 17030762.

Candow DG, Forbes SC, Roberts MD, Roy BD, Antonio J, Smith-Ryan AE, Rawson ES, Gualano B, Roschel H. Creatine O’Clock: Does Timing of Ingestion Really Influence Muscle Mass and Performance? Front Sports Act Living. 2022 May 20;4:893714. doi: 10.3389/fspor.2022.893714. PMID: 35669557; PMCID: PMC9163789.

Candow DG, Prokopidis K, Forbes SC, Rusterholz F, Campbell BI, Ostojic SM. Resistance Exercise and Creatine Supplementation on Fat Mass in Adults < 50 Years of Age: A Systematic Review and Meta-Analysis. Nutrients. 2023 Oct 12;15(20):4343. doi: 10.3390/nu15204343. PMID: 37892421; PMCID: PMC10609732.

Galvan E, Walker DK, Simbo SY, Dalton R, Levers K, O’Connor A, Goodenough C, Barringer ND, Greenwood M, Rasmussen C, Smith SB, Riechman SE, Fluckey JD, Murano PS, Earnest CP, Kreider RB. Acute and chronic safety and efficacy of dose dependent creatine nitrate supplementation and exercise performance. J Int Soc Sports Nutr. 2016 Mar 31;13:12. doi: 10.1186/s12970-016-0124-0. PMID: 27034623; PMCID: PMC4815124.

Ganguly S, Jayappa S, Dash AK. Evaluation of the stability of creatine in solution prepared from effervescent creatine formulations. AAPS PharmSciTech. 2003;4(2):E25. doi: 10.1208/pt040225. PMID: 12916907; PMCID: PMC2750587.

Harris RC, Nevill M, Harris DB, Fallowfield JL, Bogdanis GC, Wise JA. Absorption of creatine supplied as a drink, in meat or in solid form. J Sports Sci. 2002 Feb;20(2):147-51. doi: 10.1080/026404102317200855. PMID: 11811571.

Kaptsan A, Odessky A, Osher Y, Levine J. Lack of efficacy of 5 grams daily of creatine in schizophrenia: a randomized, double-blind, placebo-controlled trial. J Clin Psychiatry. 2007 Jun;68(6):881-4. doi: 10.4088/jcp.v68n0609. PMID: 17592912.

Kutz MR, Gunter MJ. Creatine monohydrate supplementation on body weight and percent body fat. J Strength Cond Res. 2003 Nov;17(4):817-21. doi: 10.1519/1533-4287(2003)017<0817:cmsobw>2.0.co;2. PMID: 14636103.

Lak M, Forbes SC, Ashtary-Larky D, Dadkhahfar S, Robati RM, Nezakati F, Khajevandi M, Naseri S, Gerafiani A, Haghighat N, Antonio J, Tinsley GM. Does creatine cause hair loss? A 12-week randomized controlled trial. J Int Soc Sports Nutr. 2025 Sep;22(sup1):2495229. doi: 10.1080/15502783.2025.2495229. Epub 2025 Apr 23. PMID: 40265319; PMCID: PMC12020143.

Lyoo IK, Yoon S, Kim TS, Hwang J, Kim JE, Won W, Bae S, Renshaw PF. A randomized, double-blind placebo-controlled trial of oral creatine monohydrate augmentation for enhanced response to a selective serotonin reuptake inhibitor in women with major depressive disorder. Am J Psychiatry. 2012 Sep;169(9):937-945. doi: 10.1176/appi.ajp.2012.12010009. PMID: 22864465; PMCID: PMC4624319.

Moriarty T, Bourbeau K, Dorman K, Runyon L, Glaser N, Brandt J, Hoodjer M, Forbes SC, Candow DG. Dose-Response of Creatine Supplementation on Cognitive Function in Healthy Young Adults. Brain Sci. 2023 Sep 1;13(9):1276. doi: 10.3390/brainsci13091276. PMID: 37759877; PMCID: PMC10526554.

Preen D, Dawson B, Goodman C, Beilby J, Ching S. Creatine supplementation: a comparison of loading and maintenance protocols on creatine uptake by human skeletal muscle. Int J Sport Nutr Exerc Metab. 2003 Mar;13(1):97-111. doi: 10.1123/ijsnem.13.1.97. PMID: 12660409.

Prokopidis K, Giannos P, Triantafyllidis KK, Kechagias KS, Forbes SC, Candow DG. Effects of creatine supplementation on memory in healthy individuals: a systematic review and meta-analysis of randomized controlled trials. Nutr Rev. 2023 Mar 10;81(4):416-427. doi: 10.1093/nutrit/nuac064. PMID: 35984306; PMCID: PMC9999677.

Sarris J, Ravindran A, Yatham LN, Marx W, Rucklidge JJ, McIntyre RS, Akhondzadeh S, Benedetti F, Caneo C, Cramer H, Cribb L, de Manincor M, Dean O, Deslandes AC, Freeman MP, Gangadhar B, Harvey BH, Kasper S, Lake J, Lopresti A, Lu L, Metri NJ, Mischoulon D, Ng CH, Nishi D, Rahimi R, Seedat S, Sinclair J, Su KP, Zhang ZJ, Berk M. Clinician guidelines for the treatment of psychiatric disorders with nutraceuticals and phytoceuticals: The World Federation of Societies of Biological Psychiatry (WFSBP) and Canadian Network for Mood and Anxiety Treatments (CANMAT) Taskforce. World J Biol Psychiatry. 2022 Jul;23(6):424-455. doi: 10.1080/15622975.2021.2013041. Epub 2022 Mar 21. PMID: 35311615.

van der Merwe J, Brooks NE, Myburgh KH. Three weeks of creatine monohydrate supplementation affects dihydrotestosterone to testosterone ratio in college-aged rugby players. Clin J Sport Med. 2009 Sep;19(5):399-404. doi: 10.1097/JSM.0b013e3181b8b52f. PMID: 19741313.


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