OxyShred Ultra Conc Review

Share this article

Watch this on YouTube.

OxyShred is sold in three main versions across North America: Non-Stim, Hardcore, and Ultra Concentrated.

oxyshred-hardcore-vs-ultra-conc-vs-non-stim — Comparison of OxyShred Hardcore vs Ultra Conc vs Non Stim ingredients

I’ve laid out the ingredient differences between all three in the chart shown here, listing everything alphabetically. Ingredients highlighted in green appear across multiple products, while red squares show what’s missing. For this review, we’re focusing specifically on the original OxyShred Ultra Concentrated and asking a straightforward question: do the ingredients it uses actually support weight loss or fat burning in a meaningful way?

Ingredients in OxyShred Ultra Concentrated

Acetyl L-Carnitine

One of the key ingredients in OxyShred Ultra Concentrated is acetyl-L-carnitine, a modified version of regular L-carnitine. Although the names sound similar, these two compounds act very differently in the body.

Acetyl-L-carnitine is primarily known for its effects on the brain and nervous system. Most research has focused on its role in cognitive function and nerve-related conditions, not fat loss. Many supplement brands blur the distinction between acetyl-L-carnitine and standard L-carnitine, assuming the benefits are interchangeable. They’re not.

While regular L-carnitine has been linked to small amounts of weight loss in some studies, acetyl-L-carnitine has not shown the same effect. So even though OxyShred Ultra Concentrated includes a form of carnitine, it’s not the version associated with improved metabolism or fat loss.

Bitter Orange Extract

Bitter orange extract became popular after ephedra was banned due to safety concerns. It contains a stimulant called synephrine, which is chemically similar to ephedrine and can increase heart rate and blood pressure.

You’ll often see bitter orange marketed as a fat-burning ingredient because it slightly raises heat production in the body. In practice, though, that increase doesn’t translate into meaningful or lasting weight loss. Clinical studies consistently show that synephrine causes cardiovascular stimulation without delivering real fat loss or performance benefits.

Caffeine

Caffeine is the most familiar ingredient in OxyShred Ultra Concentrated. It can improve alertness and slightly enhance exercise performance, which is where most of its weight-loss appeal comes from.

On its own, caffeine only produces modest fat-loss effects, mainly because it helps people move more or train harder. OxyShred provides about 150 milligrams per serving, roughly the amount found in one to two cups of coffee. That’s enough for a noticeable energy boost, but not a dramatic change in body fat.

Chromium

Chromium is often promoted as a blood-sugar regulator, but its impact on weight loss is limited. In people with insulin resistance, such as those with diabetes or PCOS, chromium can slightly improve blood sugar control and lead to very modest weight loss—usually around one to two pounds over several months.

For individuals without these conditions, however, chromium doesn’t appear to make a meaningful difference when it comes to fat loss or overall body weight.

Conjugated Linoleic Acid (CLA)

Conjugated linoleic acid, or CLA, is a type of fat that has been studied for its potential to reduce body fat. Some research suggests it may produce very small changes, typically around two to three pounds over six to twelve months.

That said, the real-world effects are modest and often unnoticeable. More importantly, effective doses of CLA are measured in grams. OxyShred Ultra Concentrated doesn’t contain nearly enough CLA to match the amounts used in those studies.

Garcinia Cambogia

Garcinia cambogia is a tropical fruit extract commonly marketed as an appetite suppressant. While a few studies have reported small weight-loss effects, those results only occur at very high doses—around five grams per day of a standardized extract.

Lower doses don’t perform better than a placebo, and most supplements, including OxyShred Ultra Concentrated, fall far short of providing that amount.

Grapefruit Seed Extract

There’s also grapefruit seed extract. One small study found that eating fresh grapefruit daily led to slight weight loss in obese adults. However, that involved consuming the equivalent of about one and a half whole grapefruits every day.

The trace amount of grapefruit seed extract found in OxyShred Ultra Concentrated is nowhere near what was used in that research, making any similar effect unlikely.

Green Coffee Bean

Green coffee beans are unroasted coffee beans that contain chlorogenic acid, a compound often claimed to support fat metabolism. Most of the evidence for this effect comes from animal studies, primarily in mice, and it’s unclear whether the same results apply to humans.

A few small human studies suggest green coffee extract may lead to minimal weight loss, but there’s a major confounding factor: these extracts also contain caffeine. That makes it difficult to separate the effects of chlorogenic acid from caffeine itself. On top of that, studies typically use doses over 500 milligrams per day, far more than what’s included in OxyShred.

Guggul

Guggul is a resin derived from a tree native to parts of India, Bangladesh, and Pakistan. Although it has a long history in traditional medicine, modern studies tell a different story.

When researchers tested guggul in people who were overweight or obese, it failed to produce meaningful or consistent weight loss.

Huperzine A

Huperzine A is an extract from plants such as Chinese club moss. It affects acetylcholine, a brain chemical involved in memory and focus.

In people with Alzheimer’s disease, huperzine A may modestly improve cognitive function. For healthy individuals without memory impairment, however, it doesn’t appear to offer noticeable benefits, especially when it comes to energy, fat loss, or weight management.

Inulin

Inulin is a type of dietary fiber that helps feed the beneficial bacteria in your gut. Because of this, it’s often linked to better digestion and improved blood sugar control. In people with prediabetes, taking inulin daily can lead to small amounts of weight loss.

However, there’s a big catch. The doses used in studies are very high—often around 30 grams per day. That’s the kind of amount you’d mix into multiple meals or smoothies, not something you’d expect from a single scoop of a supplement. The trace amounts found in OxyShred Ultra Concentrated simply aren’t enough to deliver those effects.

L-Glutamine

L-glutamine is an amino acid commonly added to workout and weight-loss supplements, but the evidence doesn’t support the hype. Studies in athletes show it doesn’t improve exercise performance. Research in people who are overweight or obese also shows no meaningful improvement in body weight or body mass index.

In other words, while L-glutamine sounds impressive on a label, it doesn’t appear to help with fat loss or body composition in real-world settings.

L-Tyrosine

L-tyrosine is another amino acid often included in energy and fat loss supplements with the hope that it will boost performance or speed up weight loss. In practice, studies show it doesn’t improve strength, endurance, or overall exercise performance.

It may help with focus and mental sharpness during stressful situations, such as intense workouts or cold exposure. But those benefits only show up at doses of several grams per day. OxyShred Ultra Concentrated contains far less than that, making any noticeable effect unlikely.

Mango Seed Extract

OxyShred includes mango seed extract, but this is not the same as African mango seed extract, which is the version sometimes studied for weight loss. Despite the similar name, these are completely different ingredients.

Even African mango has only weak evidence behind it. Regular mango seed extract, on the other hand, has no evidence at all supporting weight loss or fat burning.

Olive Leaf Extract

While olive oil gets most of the attention, olive leaves are sometimes used in supplements as well. One small study in people with metabolic syndrome found that olive leaf extract slightly improved certain metabolic markers.

That said, it did not lead to weight loss. On top of that, the doses used in the study were much higher than what you get from OxyShred Ultra Concentrated, which makes any real-world effect even less likely.

Raspberry Ketones

Raspberry ketones were once heavily marketed as a miracle fat burner, especially after being promoted on television more than a decade ago. The excitement came from lab and animal studies showing they might help mice release fat from fat cells.

The problem is that those effects were never demonstrated in humans. As people tried raspberry ketones and saw no real results, their popularity quickly faded. Despite flashy marketing, raspberry ketones have never been proven to help people lose weight.

Taurine

Taurine is an amino acid found naturally in foods like meat, seafood, and eggs, and it’s commonly added to energy and workout supplements. Some studies show it doesn’t improve endurance at all, even at fairly high doses of around five grams per day for a week.

Larger reviews suggest taurine may offer a small endurance benefit for some people when taken at doses between one and six grams per day. Once again, those are large amounts. The small dose found in OxyShred Ultra Concentrated is unlikely to make a noticeable difference.

Is OxyShred Ultra Concentrated Effective?

OxyShred Ultra Concentrated will likely make you feel more energized, mainly because it contains caffeine. When it comes to actual weight loss or fat burning, though, caffeine is essentially the only ingredient doing anything meaningful.

Many of the other ingredients sound impressive on paper but either don’t work, only work at much higher doses, or have been shown not to help at all. Ingredients like bitter orange, olive leaf extract, and raspberry ketones are often marketed as fat burners, yet the science doesn’t back those claims. Others, such as acetyl-L-carnitine, B vitamins, and taurine, are meant to support exercise performance but either don’t improve it or require doses far higher than what’s included.

By packing so many ingredients into one formula, OxyShred ends up delivering tiny, ineffective amounts of most of them. When you add proprietary blends that hide exact dosages, it becomes even harder to know what you’re actually getting—and whether it’s enough to make a real difference.

Overall Rating

Rating OxyShred Ultra Concentrated by effectiveness for weight loss, I’m giving it a C. It works about as well as drinking one or two cups of coffee, so don’t expect much unless you’re also exercising.

Rating it by cost, I’m giving it a C. The few ingredients that matter can be bought much more cheaply on their own.

Rating it for safety, I’m giving it a C. The caffeine dose is not insignificant, which can cause problems if you’re sensitive to it, and some ingredients, like bitter orange, can interact with medications.

Overall rating, I’m giving a C. It’s not something I’d recommend for most people, but if all you really want is a caffeinated pre-workout drink, it will feel similar to other heavily caffeinated weight-loss supplements—just in a tastier, drinkable form.

Top alternatives to OxyShred Ultra Concentrated

Caffeine anhydrous – 1 cap / day
Garcinia Cambogia – 1 to 5 caps / day
Taurine (caps) – 1 to 6 caps / day
Taurine (powder) – 0.25 to 1 tsp / day

Learn more about

Citations

Abboud KY, Reis SK, Martelli ME, Zordão OP, Tannihão F, de Souza AZZ, Assalin HB, Guadagnini D, Rocha GZ, Saad MJA, Prada PO. Oral Glutamine Supplementation Reduces Obesity, Pro-Inflammatory Markers, and Improves Insulin Sensitivity in DIO Wistar Rats and Reduces Waist Circumference in Overweight and Obese Humans. Nutrients. 2019 Mar 1;11(3):536. doi: 10.3390/nu11030536. PMID: 30832230; PMCID: PMC6471297.

Asbaghi O, Naeini F, Ashtary-Larky D, et al. Effects of chromium supplementation on blood pressure, body mass index, liver function enzymes and malondialdehyde in patients with type 2 diabetes: A systematic review and dose-response meta-analysis of randomized controlled trials. Complement Ther Med. 2021;60:102755. doi:10.1016/j.ctim.2021.102755

Brownley KA, Von Holle A, Hamer RM, La Via M, Bulik CM. A double-blind, randomized pilot trial of chromium picolinate for binge eating disorder: results of the Binge Eating and Chromium (BEACh) study. J Psychosom Res. 2013;75(1):36-42. doi:10.1016/j.jpsychores.2013.03.092

Collado Yurrita L, San Mauro Martín I, Ciudad-Cabañas MJ, Calle-Purón ME, Hernández Cabria M. Effectiveness of inulin intake on indicators of chronic constipation; a meta-analysis of controlled randomized clinical trials. Nutr Hosp. 2014 Aug 1;30(2):244-52. doi: 10.3305/nh.2014.30.2.7565. PMID: 25208775.

Conger SA, Tuthill LM, Millard-Stafford ML. Does Caffeine Increase Fat Metabolism? A Systematic Review and Meta-Analysis. Int J Sport Nutr Exerc Metab. 2022 Dec 10;33(2):112-120. doi: 10.1123/ijsnem.2022-0131. PMID: 36495873.

de Bock M, Derraik JG, Brennan CM, Biggs JB, Morgan PE, Hodgkinson SC, Hofman PL, Cutfield WS. Olive (Olea europaea L.) leaf polyphenols improve insulin sensitivity in middle-aged overweight men: a randomized, placebo-controlled, crossover trial. PLoS One. 2013;8(3):e57622. doi: 10.1371/journal.pone.0057622. Epub 2013 Mar 13. PMID: 23516412; PMCID: PMC3596374.

Di Stefano G, Di Lionardo A, Galosi E, Truini A, Cruccu G. Acetyl-L-carnitine in painful peripheral neuropathy: a systematic review. J Pain Res. 2019 Apr 26;12:1341-1351. doi: 10.2147/JPR.S190231. PMID: 31118753; PMCID: PMC6498091.

Fujioka K, Greenway F, Sheard J, Ying Y. The effects of grapefruit on weight and insulin resistance: relationship to the metabolic syndrome. J Med Food. 2006 Spring;9(1):49-54. doi: 10.1089/jmf.2006.9.49. PMID: 16579728.

Galloway SD, Talanian JL, Shoveller AK, Heigenhauser GJ, Spriet LL. Seven days of oral taurine supplementation does not increase muscle taurine content or alter substrate metabolism during prolonged exercise in humans. J Appl Physiol (1985). 2008 Aug;105(2):643-51. doi: 10.1152/japplphysiol.90525.2008. Epub 2008 Jun 26. PMID: 18583380.

Golzarand M, Omidian M, Toolabi K. Effect of Garcinia cambogia supplement on obesity indices: A systematic review and dose-response meta-analysis. Complement Ther Med. 2020 Aug;52:102451. doi: 10.1016/j.ctim.2020.102451. Epub 2020 May 23. PMID: 32951714.

Guess ND, Dornhorst A, Oliver N, Bell JD, Thomas EL, Frost GS. A randomized controlled trial: the effect of inulin on weight management and ectopic fat in subjects with prediabetes. Nutr Metab (Lond). 2015 Oct 24;12:36. doi: 10.1186/s12986-015-0033-2. PMID: 26500686; PMCID: PMC4619305.

Gutiérrez-Hellín J, Salinero JJ, Abían-Vicen J, Areces F, Lara B, Gallo C, Puente C, Del Coso J. Acute consumption of p-synephrine does not enhance performance in sprint athletes. Appl Physiol Nutr Metab. 2016 Jan;41(1):63-9. doi: 10.1139/apnm-2015-0299. Epub 2015 Oct 6. PMID: 26673246.

Haub MD, Potteiger JA, Nau KL, Webster MJ, Zebas CJ. Acute L-glutamine ingestion does not improve maximal effort exercise. J Sports Med Phys Fitness. 1998 Sep;38(3):240-4. PMID: 9830832.

Heymsfield SB, Allison DB, Vasselli JR, Pietrobelli A, Greenfield D, Nunez C. Garcinia cambogia (hydroxycitric acid) as a potential antiobesity agent: a randomized controlled trial. JAMA. 1998 Nov 11;280(18):1596-600. doi: 10.1001/jama.280.18.1596. PMID: 9820262.

Kanchanasurakit S, Saokaew S, Phisalprapa P, Duangjai A. Chlorogenic acid in green bean coffee on body weight: a systematic review and meta-analysis of randomized controlled trials. Syst Rev. 2023 Sep 14;12(1):163. doi: 10.1186/s13643-023-02311-4. PMID: 37710316; PMCID: PMC10503105.

Kleefstra N, Houweling ST, Jansman FG, et al. Chromium treatment has no effect in patients with poorly controlled, insulin-treated type 2 diabetes in an obese Western population: a randomized, double-blind, placebo-controlled trial. Diabetes Care. 2006;29(3):521-525. doi:10.2337/diacare.29.03.06.dc05-1453

Kleessen B, Sykura B, Zunft HJ, Blaut M. Effects of inulin and lactose on fecal microflora, microbial activity, and bowel habit in elderly constipated persons. Am J Clin Nutr. 1997 May;65(5):1397-402. doi: 10.1093/ajcn/65.5.1397. PMID: 9129468.

Koncz D, Tóth B, Bahar MA, Roza O, Csupor D. The Safety and Efficacy of Citrus aurantium (Bitter Orange) Extracts and p-Synephrine: A Systematic Review and Meta-Analysis. Nutrients. 2022 Sep 28;14(19):4019. doi: 10.3390/nu14194019. PMID: 36235672; PMCID: PMC9572433.

Liang CW, Cheng HY, Lee YH, Liou TH, Liao CD, Huang SW. Effects of conjugated linoleic acid and exercise on body composition and obesity: a systematic review and meta-analysis. Nutr Rev. 2023 Mar 10;81(4):397-415. doi: 10.1093/nutrit/nuac060. PMID: 36048508.

Mahoney CR, Castellani J, Kramer FM, Young A, Lieberman HR. Tyrosine supplementation mitigates working memory decrements during cold exposure. Physiol Behav. 2007 Nov 23;92(4):575-82. doi: 10.1016/j.physbeh.2007.05.003. Epub 2007 May 22. PMID: 17585971.

Mir TM, Ma G, Ali Z, Khan IA, Ashfaq MK. Effect of Raspberry Ketone on Normal, Obese and Health-Compromised Obese Mice: A Preliminary Study. J Diet Suppl. 2021;18(1):1-16. doi:10.1080/19390211.2019.1674996

Morimoto C, Satoh Y, Hara M, Inoue S, Tsujita T, Okuda H. Anti-obese action of raspberry ketone. Life Sci. 2005;77(2):194-204. doi:10.1016/j.lfs.2004.12.029

Ngondi JL, Etoundi BC, Nyangono CB, Mbofung CM, Oben JE. IGOB131, a novel seed extract of the West African plant Irvingia gabonensis, significantly reduces body weight and improves metabolic parameters in overweight humans in a randomized double-blind placebo controlled investigation. Lipids Health Dis. 2009 Mar 2;8:7. doi: 10.1186/1476-511X-8-7. PMID: 19254366; PMCID: PMC2651880.

Onakpoya IJ, Posadzki PP, Watson LK, Davies LA, Ernst E. The efficacy of long-term conjugated linoleic acid (CLA) supplementation on body composition in overweight and obese individuals: a systematic review and meta-analysis of randomized clinical trials. Eur J Nutr. 2012 Mar;51(2):127-34. doi: 10.1007/s00394-011-0253-9. Epub 2011 Oct 12. PMID: 21990002.

Rutherford JA, Spriet LL, Stellingwerff T. The effect of acute taurine ingestion on endurance performance and metabolism in well-trained cyclists. Int J Sport Nutr Exerc Metab. 2010 Aug;20(4):322-9. doi: 10.1123/ijsnem.20.4.322. PMID: 20739720.

Sawicka AK, Renzi G, Olek RA. The bright and the dark sides of L-carnitine supplementation: a systematic review. J Int Soc Sports Nutr. 2020 Sep 21;17(1):49. doi: 10.1186/s12970-020-00377-2. PMID: 32958033; PMCID: PMC7507632.

Solon-Júnior LJF, Boullosa Alvarez DA, Martinez Gonzalez B, da Silva Machado DG, de Lima-Junior D, de Sousa Fortes L. The effect of tyrosine supplementation on whole-body endurance performance in physically active population: A systematic review and meta-analysis including GRADE qualification. J Sports Sci. 2023 Nov;41(22):2045-2053. doi: 10.1080/02640414.2024.2309434. Epub 2024 Jan 30. PMID: 38290812.

Suksomboon N, Poolsup N, Yuwanakorn A. Systematic review and meta-analysis of the efficacy and safety of chromium supplementation in diabetes. J Clin Pharm Ther. 2014;39(3):292-306. doi:10.1111/jcpt.12147

Szapary PO, Wolfe ML, Bloedon LT, et al. Guggulipid for the Treatment of Hypercholesterolemia: A Randomized Controlled Trial. JAMA. 2003;290(6):765–772. doi:10.1001/jama.290.6.765

Tian H, Guo X, Wang X, et al. Chromium picolinate supplementation for overweight or obese adults. Cochrane Database Syst Rev. 2013;2013(11):CD010063. Published 2013 Nov 29. doi:10.1002/14651858.CD010063.pub2

Trent LK, Thieding-Cancel D. Effects of chromium picolinate on body composition. J Sports Med Phys Fitness. 1995;35(4):273-280.

Volpe SL, Huang HW, Larpadisorn K, Lesser II. Effect of chromium supplementation and exercise on body composition, resting metabolic rate and selected biochemical parameters in moderately obese women following an exercise program. J Am Coll Nutr. 2001;20(4):293-306. doi:10.1080/07315724.2001.10719050

Waldron M, Patterson SD, Tallent J, Jeffries O. The Effects of an Oral Taurine Dose and Supplementation Period on Endurance Exercise Performance in Humans: A Meta-Analysis. Sports Med. 2018 May;48(5):1247-1253. doi: 10.1007/s40279-018-0896-2. PMID: 29546641.

Wang DD, Wang TY, Yang Y, He SM, Wang YM. The Effects of L-Carnitine, Acetyl-L-Carnitine, and Propionyl-L-Carnitine on Body Mass in Type 2 Diabetes Mellitus Patients. Front Nutr. 2021 Nov 8;8:748075. doi: 10.3389/fnut.2021.748075. PMID: 34820412; PMCID: PMC8606643.

Wessinger CM, Inman CL, Weinstock J, Weiss EP. Effect of Huperzine A on Cognitive Function and Perception of Effort during Exercise: A Randomized Double-Blind Crossover Trial. Int J Exerc Sci. 2021 Aug 1;14(2):727-741. PMID: 34567353; PMCID: PMC8439683.

Yang G, Wang Y, Tian J, Liu JP. Huperzine A for Alzheimer’s disease: a systematic review and meta-analysis of randomized clinical trials. PLoS One. 2013;8(9):e74916. Published 2013 Sep 23. doi:10.1371/journal.pone.0074916