MagO7 & Oxy-Powder Review

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MagO7 and Oxy-Powder are popular colon cleanse supplements that claim to deliver an “oxygen colon cleanse.” The marketing suggests these pills gently relieve constipation by releasing oxygen directly into your digestive tract, helping flush out toxins, waste, and unwanted pathogens. It sounds advanced and highly scientific at first glance. However, once you look closer, an obvious question emerges: how much of this oxygen-based detox story actually stands up to scrutiny?

What is Ozonated Magnesium Oxide?

To understand the claim, we first need to examine what these products contain. MagO7 and Oxy-Powder use what manufacturers often call ozonated or oxygenated magnesium oxide. In practical terms, this typically means magnesium oxide blended with a small amount of magnesium peroxide. Magnesium peroxide can release oxygen when it reacts with water or acid, which explains why industries use it in agriculture, environmental cleanup, and wastewater treatment. In those settings, it acts as a slow-release oxygen source. In the human body, though, the situation looks very different.

Magnesium peroxide is known to irritate human tissue. At sufficient amounts, it may cause bloating, belching, abdominal discomfort, throat irritation, nausea, vomiting, and diarrhea. Because of these effects, oral supplements contain only tiny quantities of it. As a result, most of what you swallow in an “oxygen colon cleanse” supplement is simply magnesium oxide. Functionally, that means MagO7 and Oxy-Powder behave much like standard magnesium oxide laxatives rather than anything uniquely oxygen-driven.

Magnesium oxide itself is well understood. It works as an osmotic laxative, drawing water into the intestines, softening stool, and promoting bowel movements. Doctors and patients have used it for decades because it is inexpensive, widely available, and generally considered safe for short-term use. When people experience relief from products like MagO7 or Oxy-Powder, the effect almost certainly comes from magnesium’s laxative action, not from any meaningful oxygen delivery.

The “oxygen cleanse” concept becomes even more questionable when you consider basic chemistry. Any magnesium peroxide present reacts quickly with stomach acid, breaking down long before it could reach the lower intestines. There simply is not enough peroxide in these supplements to supply significant oxygen to the colon. If someone did ingest enough magnesium peroxide to produce substantial oxygen release in the gut, the outcome would likely involve severe irritation rather than a gentle detox experience.

Uses of Ozonated Magnesium Oxide

It is also important to ask whether oxygen release in the intestines would provide unique health benefits even in theory. Currently, there are no credible human clinical trials showing that magnesium peroxide or ozonated magnesium oxide improves constipation, digestive health, or detoxification beyond what plain magnesium oxide already offers. The limited research involving magnesium peroxide is largely experimental and typically conducted in animal models for highly specific applications, such as wound healing or bone-related studies. These findings do not translate into evidence for colon cleansing or gut detox in humans.

Outside of supplements, magnesium peroxide serves mostly industrial purposes. Environmental and engineering fields use it for soil and groundwater remediation, where it helps microorganisms break down pollutants. Wastewater treatment facilities also rely on it to increase oxygen levels and reduce odors. Swallowing it does not selectively oxygenate the body. Instead, it reacts in the stomach and converts into ordinary magnesium salts, undermining the dramatic claims often seen in supplement advertising.

Side Effects

Supporters of magnesium-based laxatives correctly note that they tend to cause less dependency than stimulant laxatives. Still, the term “gentle cleanse” can be misleading. At higher doses, magnesium oxide frequently triggers nausea, loose stools, and outright diarrhea. For many users, the experience feels less like a mild detox and more like significant gastrointestinal distress.

Safety considerations also deserve attention. Healthy kidneys typically remove excess magnesium efficiently. However, older adults and individuals with impaired kidney function face a higher risk of magnesium accumulation in the blood, a condition known as hypermagnesemia. Although uncommon, documented cases show that excessive magnesium intake can lead to serious complications. This risk becomes particularly relevant when colon cleanse supplements recommend daily doses exceeding 1,000 mg of magnesium, which is a substantial amount to consume regularly.

Dr. Brian’s Review

When you strip away the marketing, MagO7 and Oxy-Powder look a lot like dressed-up magnesium oxide supplements. Magnesium oxide itself is a well-known, inexpensive osmotic laxative that pulls water into the intestines and helps relieve constipation. From a practical standpoint, these colon cleanse products don’t behave much differently. Some versions add small amounts of electrolytes, such as potassium or citrate, and present them as a safeguard against electrolyte loss during a cleanse. In reality, unless the product is causing significant diarrhea and dehydration — which is a clear signal to stop using it — those additions rarely provide meaningful value.

Despite the “oxygen colon cleanse” claims, these supplements do not contain enough magnesium peroxide to deliver oxygen to the colon in any significant way. Most of the peroxide reacts in the stomach and breaks down long before it could reach the lower digestive tract. Even more important, the idea that added oxygen would selectively eliminate “bad” gut bacteria oversimplifies how the human microbiome actually works.

Your colon naturally operates in a very low-oxygen environment, and that is exactly what many beneficial gut bacteria require to survive. While it is true that certain harmful microbes can thrive in low-oxygen conditions, so do many of the organisms that support healthy digestion. Increasing oxygen levels in the colon has never been proven to target pathogens specifically. If anything, it could disrupt the balance of helpful bacteria along with unwanted ones.

If your primary goal is better digestive health or a healthier gut microbiome, probiotics make far more sense. Unlike ozonated magnesium oxide products, probiotics are supported by a growing body of clinical research. Numerous studies show that specific probiotic strains can help with bowel regularity, ease constipation, and promote overall gut health — benefits often promised by colon cleanse supplements without comparable evidence.

When choosing a probiotic, it is wise to focus on strains with the strongest scientific backing. Products containing Lactobacillus, Bifidobacterium, and Saccharomyces species have been studied extensively for gastrointestinal support. These strains consistently show the most reliable results for common digestive concerns.

Should You Do Colon Cleanses?

A more fundamental question remains: do you need a colon cleanse at all? Many medical professionals remain skeptical, and for good reason. The popular notion that the colon accumulates years of toxic waste that must be flushed out is not grounded in credible science. A healthy colon naturally contains a dense and diverse population of bacteria, which plays a vital role in digestion, immune function, and overall health. There is no reliable evidence that routine cleansing provides benefits beyond what normal bowel function already accomplishes.

When people feel lighter or less bloated after using a laxative or colon cleanse product, the explanation is straightforward. They have simply moved stool through the intestines. This effect reflects temporary relief from constipation, not the removal of mysterious toxins. The body already has highly effective detoxification systems, primarily the liver and kidneys.

That said, the topic deserves some nuance. Many individuals pursue colon cleanses because they want to feel better, not because they misunderstand biology. For some, “cleansing” may involve increasing dietary fiber, improving food choices, or paying closer attention to hydration. These changes can genuinely support digestion. Eating more fruits and vegetables, getting adequate fiber, and maintaining balanced meals often produce noticeable improvements in how you feel day to day.

Using laxatives when you are not constipated generally offers little benefit. However, if a short-term cleanse encourages someone to adopt healthier eating habits afterward, the long-term outcome may still be positive. The real problem lies in a common misconception: the belief that one week of a detox or colon cleanse can reverse months or years of poor dietary and lifestyle patterns. That expectation, more than the cleanse itself, is the myth worth discarding.

Top alternatives to MagO7 and Oxy-Powder

• Magnesium Citrate – 1 to 4 caps / day
• Magnesium Glycinate – 1 to 4 caps / day
• Magnesium Malate – 2 to 6 caps / day
• Magnesium Threonate – 3 to 6 caps / day
• Probiotic (Align) – 1 cap / day
• Probiotic (Culturelle) – 1 cap / day
• Probiotic (generic) – 1 cap / day

Learn more about

• Magnesium for Obesity and Diabetes
• Which Probiotics are BEST for Weight Loss?
• What Causes Bloating and Gas on a Diet?
• Dealing With Constipation On A Diet
• Best Soluble Fibers for Weight Loss
• Supplement reviews

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