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Lemon Balm Myths
Lemon balm is often touted as a natural remedy with numerous health benefits, but not all the claims hold up under scrutiny. One of the most persistent myths is that lemon balm can aid in weight loss. This belief stems from a few studies conducted on mice, where specific extracts appeared to reduce fat tissue growth and promote weight loss. However, these findings have not been replicated in human studies, and there’s no solid evidence that lemon balm affects weight or fat reduction in people.
Another common misconception is that lemon balm can effectively treat colds and the flu. Early laboratory experiments showed that lemon balm extracts had antiviral properties when tested in petri dishes or injected into eggs. While these results might sound promising, they have not translated into practical benefits for humans. Aside from certain effects on the herpes virus—which we’ll explore later—there is no clinical evidence to suggest lemon balm can help with colds, the flu, or general immune support.
Despite these myths, lemon balm does have genuine health benefits, though weight loss and cold or flu treatment aren’t among them. So, what can this herb actually do for your well-being? Let’s explore its proven advantages.
Benefits of Lemon Balm
Depression
Lemon balm may help alleviate symptoms of depression. Clinical trials reveal that taking lemon balm daily for anywhere from 3 to 56 days led to moderate improvements in depression scores compared to a control group. One small study even found that 2 grams of lemon balm appeared as effective as a low dose of Prozac—though this was only observed during the 8-week testing period.
It’s important to note that these benefits primarily come from oral extracts, not aromatherapy, and the effects are short-term, typically lasting 1–2 months. Unfortunately, the long-term impact of lemon balm on depression remains unclear.
Stress/Anxiety
Research suggests that lemon balm may reduce stress and anxiety, offering some relief in challenging situations. In one study involving healthy adults, a single 600 mg dose of lemon balm extract increased feelings of calmness during psychologically stressful tasks compared to a placebo. A smaller dose of 300 mg also showed slight improvements in anxiety, memory, and alertness during cognitive tests. Additionally, a study on people with diabetes found that daily lemon balm supplementation reduced symptoms related to anxiety and depression compared to their baseline.
As with depression, these effects are primarily linked to oral supplements rather than aromatherapy.
Cold Sores
For treating cold sores, topical lemon balm cream shows potential. Research on individuals with recurring outbreaks revealed that applying a cream containing 1% lemon balm extract at the early stages of a cold sore significantly improved healing time and reduced symptoms compared to a placebo.
Cognitive Performance
When it comes to enhancing brain function, lemon balm’s effects seem to vary depending on the individual and dosage. In one study, a single 1600 mg dose improved memory accuracy in healthy young adults but also slowed their performance on timed memory tasks. Another study showed that taking a combination product with lemon balm slightly improved word recall—but only in younger adults.
For older adults, the results were less promising. In fact, a study involving participants aged 63 and older found no cognitive benefits from lemon balm after 96 weeks of daily supplementation. This suggests that lemon balm may not help with age-related cognitive decline.
Dementia
Lemon balm may help reduce agitation in dementia patients, though its impact on cognitive performance is minimal. One small study involving elderly patients with mild to moderate Alzheimer’s disease found that taking 60 drops of lemon balm extract daily reduced agitation compared to a placebo. Similarly, another study on mild Alzheimer’s patients showed slight improvements in agitation with daily lemon balm use, though cognitive function remained unchanged.
Aromatherapy with lemon balm has also been explored, but it appears less effective than oral extracts. For instance, in one study, applying lemon balm-infused lotion to the hands and faces of patients with severe dementia slightly reduced agitation. However, researchers noted that the result might have been influenced by the physical touch and social interaction involved in applying the lotion, rather than the lemon balm itself. Supporting this, a separate study found that massaging lemon balm oil on Alzheimer’s patients twice daily didn’t reduce agitation more than a placebo oil—indicating that the act of massage, not the oil, made the difference. Similarly, inhaling lemon balm oil for two hours daily showed no reduction in agitation.
In summary, lemon balm extracts may help ease agitation when taken orally, but their effects on cognitive function are limited. Aromatherapy with lemon balm offers less consistent results and often depends on factors like touch and interaction rather than the properties of the herb itself.
Digestive Health
Lemon balm is often included in products designed to relieve digestive issues, though its individual effects can be hard to isolate. For infants with colic, multi-ingredient products containing lemon balm have been shown to reduce crying times when given orally.
In adults with Irritable Bowel Syndrome (IBS), combination products like Iberogast, which include lemon balm, have demonstrated an ability to ease symptoms such as acid reflux, stomach pain, and nausea compared to a placebo. Another product, Carmint, taken after meals, further reduced abdominal pain and discomfort when combined with standard IBS treatments like loperamide or psyllium.
While promising, these results primarily apply to lemon balm as part of a blend, making it unclear how much of the benefit is due to the herb itself.
Sleep
Lemon balm may also improve sleep quality, but like its use for digestion, it’s often part of a combination of herbs, which complicates pinpointing its exact effects. In adults, specific products containing lemon balm extract have been found to enhance both sleep quality and quantity.
For children under 12, similar multi-ingredient remedies have shown promise in reducing restlessness and helping them fall asleep faster compared to their baseline sleep patterns.
While lemon balm appears beneficial for sleep, more research is needed to confirm its standalone effects, as most studies focus on herbal blends.
Summary
Lemon balm shows potential in helping with stress, anxiety, depression, and reducing agitation in dementia patients. However, the evidence supporting these benefits isn’t particularly strong. It may also aid digestion and improve sleep, but since most studies involve lemon balm combined with other ingredients, its solo effectiveness remains uncertain.
This versatile herb is commonly used in two forms: oil extracts and leaf extracts. Oil extracts are often used in aromatherapy for their calming scent, making them a popular choice for relaxation. Leaf extracts, on the other hand, are rich in antioxidants like flavonoids and polyphenols and are typically used in teas and oral supplements. While lemon balm teas may provide general health benefits, the most significant effects appear to come from standardized oral extracts, particularly those standardized to rosmarinic acid. This compound is also found in other culinary herbs like rosemary, sage, and basil.
Non-standardized forms, such as generic extracts or tinctures, are less likely to deliver the same results. Additionally, while lemon balm aromatherapy may offer a pleasant aroma, it doesn’t seem to provide the same health benefits as oral extracts.
Top supplement choices
- Lemon Balm – 1 to 2 caps / day
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Citations
A. Cerny, K. Schmid. Tolerability and efficacy of valerian/lemon balm in healthy volunteers (a double-blind, placebo-controlled, multicentre study),Fitoterapia,Volume 70, Issue 3,1999,Pages 221-228,ISSN 0367-326X
Akhondzadeh S, Noroozian M, Mohammadi M, Ohadinia S, Jamshidi AH, Khani M. Melissa officinalis extract in the treatment of patients with mild to moderate Alzheimer’s disease: a double blind, randomised, placebo controlled trial. J Neurol Neurosurg Psychiatry. 2003 Jul;74(7):863-6. doi: 10.1136/jnnp.74.7.863. PMID: 12810768; PMCID: PMC1738567.
Araj-Khodaei M, Noorbala AA, Yarani R, Emadi F, Emaratkar E, Faghihzadeh S, Parsian Z, Alijaniha F, Kamalinejad M, Naseri M. A double-blind, randomized pilot study for comparison of Melissa officinalis L. and Lavandula angustifolia Mill. with Fluoxetine for the treatment of depression. BMC Complement Med Ther. 2020 Jul 3;20(1):207. doi: 10.1186/s12906-020-03003-5. PMID: 32620104; PMCID: PMC7333290.
Ballard CG, O’Brien JT, Reichelt K, Perry EK. Aromatherapy as a safe and effective treatment for the management of agitation in severe dementia: the results of a double-blind, placebo-controlled trial with Melissa. J Clin Psychiatry. 2002 Jul;63(7):553-8. doi: 10.4088/jcp.v63n0703. PMID: 12143909.
Behzadi A, Imani S, Deravi N, Mohammad Taheri Z, Mohammadian F, Moraveji Z, Shavysi S, Mostafaloo M, Soleimani Hadidi F, Nanbakhsh S, Olangian-Tehrani S, Marabi MH, Behshood P, Poudineh M, Kheirandish A, Keylani K, Behfarnia P. Antiviral Potential of Melissa officinalis L.: A Literature Review. Nutr Metab Insights. 2023 Jan 12;16:11786388221146683. doi: 10.1177/11786388221146683. PMID: 36655201; PMCID: PMC9841880.
Burns A, Perry E, Holmes C, Francis P, Morris J, Howes MJ, Chazot P, Lees G, Ballard C. A double-blind placebo-controlled randomized trial of Melissa officinalis oil and donepezil for the treatment of agitation in Alzheimer’s disease. Dement Geriatr Cogn Disord. 2011;31(2):158-64. doi: 10.1159/000324438. Epub 2011 Feb 19. PMID: 21335973.
Dimitrova Z, Dimov B, Manolova N, Pancheva S, Ilieva D, Shishkov S. Antiherpes effect of Melissa officinalis L. extracts. Acta Microbiol Bulg. 1993;29:65-72. PMID: 8390134.
Ghazizadeh J, Sadigh-Eteghad S, Marx W, Fakhari A, Hamedeyazdan S, Torbati M, Taheri-Tarighi S, Araj-Khodaei M, Mirghafourvand M. The effects of lemon balm (Melissa officinalis L.) on depression and anxiety in clinical trials: A systematic review and meta-analysis. Phytother Res. 2021 Dec;35(12):6690-6705. doi: 10.1002/ptr.7252. Epub 2021 Aug 27. PMID: 34449930.
Kennedy DO, Little W, Scholey AB. Attenuation of laboratory-induced stress in humans after acute administration of Melissa officinalis (Lemon Balm). Psychosom Med. 2004 Jul-Aug;66(4):607-13. doi: 10.1097/01.psy.0000132877.72833.71. PMID: 15272110.
Kennedy DO, Wake G, Savelev S, Tildesley NT, Perry EK, Wesnes KA, Scholey AB. Modulation of mood and cognitive performance following acute administration of single doses of Melissa officinalis (Lemon balm) with human CNS nicotinic and muscarinic receptor-binding properties. Neuropsychopharmacology. 2003 Oct;28(10):1871-81. doi: 10.1038/sj.npp.1300230. PMID: 12888775.
Kim MY, Park BY, Lee HS, Park EK, Hahm JC, Lee J, Hong Y, Choi S, Park D, Lee H, Yoon M. The anti-angiogenic herbal composition Ob-X inhibits adipose tissue growth in obese mice. Int J Obes (Lond). 2010 May;34(5):820-30. doi: 10.1038/ijo.2010.13. Epub 2010 Feb 23. Erratum in: Int J Obes (Lond). 2010 Aug;34(8):1354. PMID: 20179671.
Koytchev R, Alken RG, Dundarov S. Balm mint extract (Lo-701) for topical treatment of recurring herpes labialis. Phytomedicine. 1999 Oct;6(4):225-30. doi: 10.1016/S0944-7113(99)80013-0. PMID: 10589440.
Kucera LS, Cohen RA, Herrmann EC Jr. Antiviral activities of extracts of the lemon balm plant. Ann N Y Acad Sci. 1965 Jul 30;130(1):474-82. doi: 10.1111/j.1749-6632.1965.tb12584.x. PMID: 4285591.
Lee D, Shin Y, Roh JS, Ahn J, Jeoong S, Shin SS, Yoon M. Lemon Balm Extract ALS-L1023 Regulates Obesity and Improves Insulin Sensitivity via Activation of Hepatic PPARα in High-Fat Diet-Fed Obese C57BL/6J Mice. Int J Mol Sci. 2020 Jun 15;21(12):4256. doi: 10.3390/ijms21124256. PMID: 32549364; PMCID: PMC7352304.
Melzer J, Rösch W, Reichling J, Brignoli R, Saller R. Meta-analysis: phytotherapy of functional dyspepsia with the herbal drug preparation STW 5 (Iberogast). Aliment Pharmacol Ther. 2004 Dec;20(11-12):1279-87. doi: 10.1111/j.1365-2036.2004.02275.x. PMID: 15606389.
Müller SF, Klement S. A combination of valerian and lemon balm is effective in the treatment of restlessness and dyssomnia in children. Phytomedicine. 2006 Jun;13(6):383-7. doi: 10.1016/j.phymed.2006.01.013. Epub 2006 Feb 17. PMID: 16487692.
Noguchi-Shinohara M, Hamaguchi T, Sakai K, Komatsu J, Iwasa K, Horimoto M, Nakamura H, Yamada M, Ono K. Effects of Melissa officinalis Extract Containing Rosmarinic Acid on Cognition in Older Adults Without Dementia: A Randomized Controlled Trial. J Alzheimers Dis. 2023;91(2):805-814. doi: 10.3233/JAD-220953. PMID: 36502333.
Noguchi-Shinohara M, Ono K, Hamaguchi T, Nagai T, Kobayashi S, Komatsu J, Samuraki-Yokohama M, Iwasa K, Yokoyama K, Nakamura H, Yamada M. Safety and efficacy of Melissa officinalis extract containing rosmarinic acid in the prevention of Alzheimer’s disease progression. Sci Rep. 2020 Oct 29;10(1):18627. doi: 10.1038/s41598-020-73729-2. PMID: 33122694; PMCID: PMC7596544.
Perry NSL, Menzies R, Hodgson F, Wedgewood P, Howes MR, Brooker HJ, Wesnes KA, Perry EK. A randomised double-blind placebo-controlled pilot trial of a combined extract of sage, rosemary and melissa, traditional herbal medicines, on the enhancement of memory in normal healthy subjects, including influence of age. Phytomedicine. 2018 Jan 15;39:42-48. doi: 10.1016/j.phymed.2017.08.015. Epub 2017 Aug 18. PMID: 29433682.
Safari M, Asadi A, Aryaeian N, Huseini HF, Shidfar F, Jazayeri S, Malek M, Hosseini AF, Hamidi Z. The effects of melissa officinalis on depression and anxiety in type 2 diabetes patients with depression: a randomized double-blinded placebo-controlled clinical trial. BMC Complement Med Ther. 2023 May 2;23(1):140. doi: 10.1186/s12906-023-03978-x. PMID: 37131158; PMCID: PMC10152712.
Savino F, Cresi F, Castagno E, Silvestro L, Oggero R. A randomized double-blind placebo-controlled trial of a standardized extract of Matricariae recutita, Foeniculum vulgare and Melissa officinalis (ColiMil) in the treatment of breastfed colicky infants. Phytother Res. 2005 Apr;19(4):335-40. doi: 10.1002/ptr.1668. PMID: 16041731.
Scholey A, Gibbs A, Neale C, Perry N, Ossoukhova A, Bilog V, Kras M, Scholz C, Sass M, Buchwald-Werner S. Anti-stress effects of lemon balm-containing foods. Nutrients. 2014 Oct 30;6(11):4805-21. doi: 10.3390/nu6114805. PMID: 25360512; PMCID: PMC4245564.
Vejdani R, Shalmani HR, Mir-Fattahi M, Sajed-Nia F, Abdollahi M, Zali MR, Mohammad Alizadeh AH, Bahari A, Amin G. The efficacy of an herbal medicine, Carmint, on the relief of abdominal pain and bloating in patients with irritable bowel syndrome: a pilot study. Dig Dis Sci. 2006 Aug;51(8):1501-7. doi: 10.1007/s10620-006-9079-3. Epub 2006 Jul 26. PMID: 16868824.
Watson K, Hatcher D, Good A. A randomised controlled trial of Lavender (Lavandula Angustifolia) and Lemon Balm (Melissa Officinalis) essential oils for the treatment of agitated behaviour in older people with and without dementia. Complement Ther Med. 2019 Feb;42:366-373. doi: 10.1016/j.ctim.2018.12.016. Epub 2018 Dec 21. PMID: 30670268.
Yoon M, Kim MY. The anti-angiogenic herbal composition Ob-X from Morus alba, Melissa officinalis, and Artemisia capillaris regulates obesity in genetically obese ob/ob mice. Pharm Biol. 2011 Jun;49(6):614-9. doi: 10.3109/13880209.2010.539617. PMID: 21554004.
Attributions
Lemon balm plant (Melissa officinalis), ladybird included for scale By Amitchell125 – Own work, CC BY-SA 4.0, https://commons.wikimedia.org/w/index.php?curid=106078428
See also
- Real Benefits of Lemon BalmLemon balm may help with mental health issues like depression and stress and could also aid in treating cold sores.
- Real Benefits of LysineThere is no evidence that lysine helps in weight loss. In fact, the opposite is true, as taking lysine could lead to weight gain.
- Kava vs AlcoholKava is a safer alternative to alcohol for those seeking relaxation, as research suggests it is effective in managing everyday anxiety.
- The Benefits of InositolInositol, particularly a 40:1 myo- to D-chiro ratio, supports fertility in PCOS, but myo-inositol alone works well for most other uses.
- The Benefits of L-TheanineL-theanine is known for enhancing focus and reducing stress but may not be as effective for anxiety and sleep.