Doctor Reviews: Arrae MB-1

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Arrae MB-1 claims to help burn fat and curb cravings with what it calls “natural faux-zempic.” But what exactly is “faux-zempic”? Essentially, it’s a marketing term meant to suggest similarities to Ozempic—without actually being Ozempic. That’s like calling a Honda Civic a “faux-Ferrari.”

Before diving into the ingredients, let’s take a look at what real customers are saying. On Trustpilot, Arrae has a 2.3-star rating, officially marked as “Poor.” That’s not a great start. A quick scroll through the reviews reveals that most are 1-star. Over on ThingTesting, things don’t look much better—only 38% of reviewers say they’d recommend it to a friend. Again, 1-star reviews dominate.

Now, onto the real question: do the ingredients actually do anything? Let’s break them down.

Ingredients of Arrae MB-1

Vitamin B6

Vitamin B6 has been loosely studied in relation to weight loss, particularly in women, but the evidence remains weak. One small clinical trial found that taking 80 mg of B6 daily for eight weeks led to a slight reduction in fat mass. However, Arrae MB-1 only contains 5 mg—nowhere near the amount used in the study. In other words, it’s unlikely to have any real impact.

Chromium

Chromium is often marketed as a blood sugar regulator, but does it actually help with weight loss? For individuals with diabetes, chromium may slightly lower blood sugar levels (HbA1C by about 0.6%) and lead to modest weight loss—about half a kilo to a kilo over 12 to 16 weeks. However, these benefits are mostly seen in people with insulin resistance, such as those with diabetes or PCOS. For those without these conditions, research suggests chromium has little to no effect on weight loss.

And what about cravings? Many brands claim chromium is “clinically studied” for reducing cravings, but there’s a catch—no clinical studies have tested that claim in healthy individuals. The closest research available looked at chromium’s effects on people with binge eating disorder, a condition characterized by intense cravings and compulsive overeating. The result? Chromium had no impact on binge eating frequency, body weight, or mood.

So, the claim that chromium is proven to help with cravings? Completely false. Not only is there no supporting research in healthy people, but even in those with binge eating disorder, chromium didn’t make a difference.

Green Tea Extract

Green tea extract is often marketed as a fat-burning powerhouse, thanks to compounds called catechins—especially EGCG. But for it to have any real impact, you need a high dose. A meta-analysis of 25 trials found that people taking green tea with caffeine lost an average of 1.8 kg. Sounds promising, right? The catch is that this effect was only seen in those taking 500 to 800 mg of EGCG per day. Lower doses don’t seem to make much of a difference in weight or fat loss.

African Mango Seed

African mango seed is another ingredient often linked to weight management. Some studies suggest that a specific extract, IGOB131, might help with weight loss when taken before meals. However, most of these studies were poorly designed and all conducted by the same researcher—raising serious concerns about bias. Independent research that isn’t connected to this researcher has found that IGOB131 doesn’t significantly reduce body weight or fat mass.

Cissus Leaf

Cissus quadrangularis, particularly an extract called CQR-300, has been tested in small clinical trials for obesity. A meta-analysis suggests that taking CQR-300 before meals may slightly lower body weight compared to a placebo. In one study, participants who took it for eight weeks saw a modest 13% reduction in body fat—while the placebo group saw no change.

Grains of Paradise

Grains of Paradise, a spice from the ginger family, is sometimes promoted as a weight loss aid. However, research suggests it has little to no real effect. One small study with just 19 participants looked at its impact on metabolism and fat loss. While those taking the extract saw a small reduction in visceral fat, there were no changes in subcutaneous fat, body fat percentage, or total weight. In fact, the placebo group lost more weight overall, though the difference wasn’t statistically significant. Other studies confirm that Grains of Paradise likely doesn’t contribute to meaningful weight or fat loss.

Bifidobacterium lactis B420

Bifidobacterium lactis B420 is another ingredient in Arrae MB-1. Some probiotic strains of Bifidobacterium lactis have been studied for their potential effects on obesity, with CECT 8145 showing slight BMI reductions after three months. However, Arrae MB-1 contains a different strain—Bifidobacterium lactis B420. Clinical research on this specific strain found that taking it for six months had no effect on body fat or weight compared to a placebo.

Is Arrae MB-1 Effective?

Based on the available research, Arrae MB-1 is unlikely to have a meaningful impact on weight or fat loss.

While it includes ingredients like Vitamin B6 and chromium, their effects on weight are minimal unless someone has a metabolic condition. Even then, the benefits are small. Green tea extract and Cissus quadrangularis might help slightly, but only in high doses—typically hundreds of milligrams of specialized extracts. Since Arrae MB-1 doesn’t disclose exact dosages, it’s impossible to determine whether the ingredients are present in effective amounts. Other ingredients, such as African mango seed, Grains of Paradise, and Bifidobacterium lactis B420, lack strong, independent evidence supporting their role in weight loss.

Overall Rating

Rating Arrae MB-1 by effectiveness for weight loss, I’m giving it a C. Some of its ingredients might have minor weight-loss benefits, but since the exact doses aren’t disclosed, there’s no way to know if they’re included in amounts that actually work.

Rating it by cost, I’m giving it an D. You could easily recreate the formula using individual ingredients for a fraction of the price.

Rating it for safety, I’m giving it a C. While green tea extract is generally safe, high doses have been linked to liver issues in rare cases. Since they don’t disclose how much green tea extract it contains, there’s no way to know if the amount is within a safe range.

Overall rating, I’m giving a D. I would not recommend it at all.

Top alternatives to Arrae MB-1

• Cissus quadrangularis – 1 to 2 caps / day
• Green tea (caps) – 2 to 4 caps / day
• Green tea (Hyleys) – 1 to 2 cups / day
• Green tea (teabags, decaf) – 1 to 4 cups / day
• Green tea (teabags) – 1 to 4 cups / day
• Vitamin B6 – 1 to 2 caps / day

Learn more about

• African Mango for Weight Loss
• Chromium For Weight Loss
• Green Tea For Weight Loss
• Which Probiotics are BEST for Weight Loss?
• Supplement reviews

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  Doctor Reviews: Lipo Gummies
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  Doctor Reviews: Arrae MB-1
  Arrae MB-1 is unlikely to cause significant weight loss and can be cheaply replicated with individual ingredients.
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  Doctor Reviews: WEEM Hair Skin and Nails
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